Audio Qbank – HY USMLE Q #353 – Hematology

Ten hours following circumcision, a 4-day-old boy has persistent bleeding at the circumcision site. He was born at term following an uncomplicated pregnancy and delivery. Examination shows a left temporal cephalohematoma. Laboratory studies show:

Platelet count                                                   300,000/μL
Bleeding time                                                    5 minutes
Prothrombin time                                          14 seconds
Partial thromboplastin time                    52 seconds

Which of the following is the most likely explanation for these findings?

Bernard-Soulier syndrome
Glanzmann thrombasthania
Hemophilia
Vitamin K deficiency
von Willebrand disease