Audio Qbank – HY USMLE Q #435 – Endocrine / Repro

A 24-year-old woman comes to the physician because she has not had a menstrual period for 8 months. Menarche was at the age of 12 years and cycles had initially been at regular 28-day interval. Two years ago, menses began occurring irregularly at 40-80-day intervals before finally ceasing altogether. She has no past medical history and takes no medications. She does not smoke, drink, or use drugs. She runs 10 miles daily and has competed in four marathons the past year. Her BMI is 17. Physical examination shows no abnormalities. Which of the following combinations of estrogen, luteinizing hormone (LH), and follicle-stimulating hormone (FSH)  is most likely to be seen in this patient?

↑ Estrogen; ↑ LH; ↑ FSH
↑ Estrogen; ↑ LH; ↓ FSH
↑ Estrogen; ↓ LH; ↑ FSH
↑ Estrogen; ↓ LH; ↓ FSH
↓ Estrogen; ↑ LH; ↑ FSH
↓ Estrogen; ↑ LH; ↓ FSH
↓ Estrogen; ↓ LH; ↑ FSH
↓ Estrogen; ↓ LH; ↓ FSH