A 49-year-old woman with long-standing rheumatoid arthritis comes to the physician for a routine health maintenance examination. Current medications are high-dose ibuprofen, prednisone, and methotrexate. She has a 25-pack-year history of smoking. Physical examination shows central obesity with violaceous striae. Serum potassium is 3.3 mEq/L (NR 3.5-5.0). A chest x-ray shows mild hyperinflation. Which of the following combinations of findings is most likely to be seen in this patient?
↑ ACTH release from anterior pituitary; ↑ ACTH release from pulmonary neoplasm; ↑ Serum cortisol
↑ ACTH release from anterior pituitary; ↑ ACTH release from pulmonary neoplasm; ↓ Serum cortisol
↑ ACTH release from anterior pituitary; ↓ ACTH release from pulmonary neoplasm; ↑ Serum cortisol
↑ ACTH release from anterior pituitary; ↓ ACTH release from pulmonary neoplasm; ↓ Serum cortisol
↓ ACTH release from anterior pituitary; ↑ ACTH release from pulmonary neoplasm; ↑ Serum cortisol
↓ ACTH release from anterior pituitary; ↑ ACTH release from pulmonary neoplasm; ↓ Serum cortisol
↓ ACTH release from anterior pituitary; ↓ ACTH release from pulmonary neoplasm; ↑ Serum cortisol
↓ ACTH release from anterior pituitary; ↓ ACTH release from pulmonary neoplasm; ↓ Serum cortisol
