Audio Qbank – HY USMLE Q #507 – Weird renal but on NBME

A 54-year-old man comes to the physician for a 2-week history of increased urinary frequency and thirst. Vitals are within normal limits. Mucous membranes are dry. Serum calcium is 14.1 mg/dL and serum phosphorus is 2.2 mg/dL. Which of the following is the most likely explanation for this patient’s volume depletion and polyuria?

Bartter syndrome
Chronic pyelonephritis
Gitelman syndrome
Interstitial nephropathy
Nephrogenic diabetes insipidus