A 69-year-old woman comes to the physician for a 3-week history of epigastric pain during meals. She has been taking high-dose naproxen for the past 6 weeks to treat her osteoarthritis. Which of the following is the most appropriate pharmacologic treatment for this patient?
Bismuth
Cimetidine
Dinoprostone
Esomeprazole
Loratadine
Misoprostol
