Audio Qbank – HY USMLE Q #559 – Hematology

A 69-year-old male comes to the physician for a 4-month history of generalized pruritus and occasional headaches. Blood pressure is 125/75. BMI is 30. Laboratory studies show:

Hemoglobin                                                                         19 g/dL
WBC                                                                                         9,000/μL
Platelets                                                                                 400,000/μL
Arterial O2 saturation                                                   93% on room air
Red cell distribution width                                         Normal
Creatinine                                                                            1.2 mg/dL

Which of the following is most likely to be seen in this patient?

Anemia
Carboxyhemoglobin
Dacryocytosis
Increased HbA2 and HbF
Megakaryocytic hyperplasia
Mutation in JAK2