A 69-year-old male comes to the physician for a 4-month history of generalized pruritus and occasional headaches. Blood pressure is 125/75. BMI is 30. Laboratory studies show:
Hemoglobin 19 g/dL
WBC 9,000/μL
Platelets 400,000/μL
Arterial O2 saturation 93% on room air
Red cell distribution width Normal
Creatinine 1.2 mg/dL
Which of the following is most likely to be seen in this patient?