A 63-year-old man is admitted to hospital for acute exacerbation of COPD. He is disoriented and has wide-based ataxic gait. Examination shows weakness of abduction of both eyes and nystagmus on lateral gaze. The deficiency substrate in this patient is normally a cofactor for which of the following?
Conversion of pyruvate to oxaloacetate
Conversion of succinate to fumarate
DNA synthesis
δ-aminolevulinic acid synthesis
Succinyl-CoA synthesis
