HY USMLE Q #655 – Pathology

A 6-year-old girl is brought to hospital by her father after an episode in which she suddenly fell to the ground and convulsed. She has a 3-week history of behavioral disturbances and personality change. Her right knee is swollen and painful. Hemoglobin is 10 g/dL, WBCs 3,500/μL, platelets 50,000/μL. A Coombs test is positive. Urinalysis shows blood and protein. Which of the following is the most likely diagnosis?

Beckwith-Wiedemann syndrome
Denys-Drash syndrome
Membranoproliferative glomerulonephritis
Systemic lupus erythematosus
WAGR syndrome