A 66-year-old man comes to the physician for a 4-month history of pelvic pain. He has lost 10 pounds during this time despite no change in diet. X-ray and MRI of the pelvis demonstrate a mass. Biopsy confirms the diagnosis. A mutation in which of the following genes is most likely to be seen in this patient?
BRCA1
DMD
FXN (Frataxin)
FMR1
IDH1