A 39-year-old woman comes to the physician for a health maintenance examination. She has no past medical history. She plans to attend a family event on a yacht next week and is concerned about sea sickness. The physician prescribes a stat dose of diphenhydramine. Binding at which of the following receptors is most likely responsible for prevention of motion sickness in this patient?
α1 antagonism
D1 antagonism
D2 antagonism
H2 antagonism
M3 antagonism