A 34-year-old woman comes to the clinic for follow-up of her persistent asthma. She reports nightly coughing and occasional wheezing despite regular use of an albuterol inhaler. She was recently started on zafirlukast. Since starting the medication, she has noticed a reduction in symptoms and better sleep. Her past medical history is significant for seasonal allergic rhinitis. Pulmonary function tests show a mild obstructive pattern with improvement after bronchodilator administration. Which of the following is most likely true of this patient’s new pharmacologic therapy?
Blocks lipoxygenase synthesis; decreases bronchoconstriction
Blocks lipoxygenase synthesis; decreases vasoconstriction
Blocks LTB4; decreases bronchoconstriction
Blocks LTC4; decreases vasoconstriction
Decreases arachidonic acid effects; ideal for aspirin hypersensitivity
Decreases arachidonic acid effects; ideal for seasonal allergies
Blocks lipoxygenase synthesis; decreases vasoconstriction
Blocks LTB4; decreases bronchoconstriction
Blocks LTC4; decreases vasoconstriction
Decreases arachidonic acid effects; ideal for aspirin hypersensitivity
Decreases arachidonic acid effects; ideal for seasonal allergies

