A 53-year-old man comes to the physician for a 4-month history of daytime fatigue and swelling of the left axilla. He also is concerned about some areas of purple blotching on the arms despite no recent traumas.

Which of the following is most likely to be seen in this patient?
A) Breakpoint cluster region abnormality
B) CD10 positivity
C) JAK/STAT tyrosine kinase misconfiguration
D) Primary activation of MAP tyrosine kinase
E) Retinoic acid receptor alpha fusion protein

