A 21-year-old man comes to the physician for a 3-day history of darkening of his urine. There is no associated pain. Physical examination shows the use of hearing aids. Visual examination is unremarkable.

Which of the following is most likely to be seen in this patient?
A) Antibodies against the alpha-3 chains of type-4 collagen
B) Spike and dome appearance
C) Splitting and lamellation of basement membranes
D) Subendothelial deposits
E) Subepithelial deposits

