HY USMLE Q #1658 – Immuno

A 15-year-old boy is brought to the physician for a 2-day history of loose, foul-smelling stools. He has a long history of pneumonia, sinusitis, and otitis media since childhood. Current medications include albuterol and fluticasone inhalers. His mother had an episode of deQuervain thyroiditis last year. Results of a stool sample are shown.

Which of the following is the most likely explanation for this patient’s findings?

A) Deficiency of CD40-Ligand
B) Deficiency of cell-mediated immunity
C) Deficiency of mucosal immunoglobulin
D) IL-2 receptor mutation
E) Tyrosine kinase mutation

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