A 72-year-old woman is brought to hospital two hours after developing shortness of breath with exertion. She has a history of ischemic heart disease. Her vitals are: temperature 99.0F, HR 120, RR 16, BP 110/60. An ECG shows absent P-waves. Intravenous dofetilide is administered. Seven minutes later, an ECG shows sinus rhythm. This patient is at greatest risk for which of the following adverse drug effects within the next several hours?
Delta-waves
PR-interval >200 ms
Flattened T-waves + U-waves
Tented T-waves
Sinusoidal rhythm
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Cut-to-the-chase Answer (0:38):
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HY USMLE Answer (3:41):