A 44-year-old man comes to the GP because of a 4-month history of worsening shortness of breath. Examination shows JVD and a loud P2. Spirometry shows an FEV1/FVC of 34% and a decreased DLCO. Which of the following is most likely decreased in this patient’s pulmonary vascular smooth muscle?
Diacylglycerol
Endothelin-1
Nitric oxide synthase
Thrombomodulin
Vascular endothelial growth factor
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Cut-to-the-chase Answer (0:36):
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HY USMLE Answer (5:09):