A 26-year-old man is brought to the emergency department because of a one-week history of productive cough, fever, and chills. He has a 4-year history of multiple episodes of pneumonia, bronchitis, and sinusitis. He has been married for two years. Since that time, his wife has been unable to conceive. His vitals are: temperature 102.1F, HR 90, RR 22, BP 120/80. His chest x-ray is shown. This patient most likely has a defect in which of the following?
Chloride channel (unidirectional)
Chloride-bicarbonate channel (bidirectional)
Dynein
Secretory immunoglobulin
Tyrosine kinase
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Cut-to-the-chase Answer (1:52):
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HY USMLE Answer (4:48):