Audio Qbank – Q140 – A 57M with generalized tiredness

 

A 57-year-old man presents to the physician for a routine health maintenance examination. He reports generalized tiredness. BMI is 27. Thyroid function studies show a TSH of 6.7 mIU/L (NR 0.5-5.0); serum T3 and T4 are within normal limits. Antibody screening is performed and is negative. Which of the following is the most appropriate management for this patient?

 

  One-week trial of thyroxine at 25% dosing
  One-week trial of thyroxine at 50% dosing
  One-week trial of propylthiouracil at 25% dosing
  One-week trial of propylthiouracil at 50% dosing
  Two-week trial of thyroxine at 25% dosing
  Two-week trial of thyroxine at 50% dosing
  Two-week trial of propylthiouracil at 25% dosing
  Two-week trial of propylthiouracil at 50% dosing
  Schedule follow-up appointment in 3 months

 

Cut-to-the-chase Answer (0:57):