Audio Qbank – Q149 – A 58M with high calcium

 

A 58-year-old man presents to the physician for a 4-month history of fatigue. He has lost 20 pounds over this time despite no changes in diet or exercise. He has a 40-pack-year history of smoking. Serum calcium is 12.0 mEq/L (NR 8.4-10.2). He is afebrile. Vitals are stable and within normal limits. Which of the following combinations of findings is most likely in this patient?

 

↑ PTH; ↑ 24,25-(OH)2-Vitamin D3; ↑ Fecal calcium
↑ PTH; ↑ 24,25-(OH)2-Vitamin D3; ↓ Fecal calcium
↑ PTH; ↓ 24,25-(OH)2-Vitamin D3; ↑ Fecal calcium
↑ PTH; ↓ 24,25-(OH)2-Vitamin D3; ↓ Fecal calcium
↓ PTH; ↑ 24,25-(OH)2-Vitamin D3; ↑ Fecal calcium
↓ PTH; ↑ 24,25-(OH)2-Vitamin D3; ↓ Fecal calcium
↓ PTH; ↓ 24,25-(OH)2-Vitamin D3; ↑ Fecal calcium
↓ PTH; ↓ 24,25-(OH)2-Vitamin D3; ↓ Fecal calcium

 

Cut-to-the-chase Answer (1:12):
HY USMLE Answer (3:11):