A 29-year-old woman comes to the physician because of a 2-year history of irregular menses. Blood pressure is 115/60. Physical examination shows hair growth above the lip and on the chest. Pelvic examination shows clitoromegaly. Serum DHEA-S is 660 ug/dL (NR: 65-380). Which of the following enzymes is most likely deficient in this patient?
11β-hydroxylase
17α-hydroxylase
21-hydroxylase
ACTH
Desmolase
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Cut-to-the-chase Answer (0:30):
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HY USMLE Answer (4:38):