A 52-year-old woman comes to the physician because of a 10-month history of hot flashes and menstrual irregularity. Her mother has osteoporosis. Weight-bearing exercise is recommended as well as calcium and vitamin D supplements. The patient asks about a drug called alendronate that her mother is taking. Which of the following is the mechanism of action of this agent?
Inhibition of RANK-L
Inhibition of RANK receptor
Inhibition of osteoclast activity
Stimulation of 1α hydroxylation of calcidiol
Stimulation of osteoblast activity
Stimulation of osteoprotegerin (OPG)
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Cut-to-the-chase Answer (0:31):
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HY USMLE Answer (5:53):
