A 68-year-old man comes to the GP because of a one-week history of blistering. Examination shows tense bullae and sloughing of the skin across the chest, abdomen, and arms. There are no oral lesions. A skin biopsy is performed and immunofluorescence shows a net-like pattern. Which of the following is the most likely target of the autoantibodies produced by this patient?
Adherens junction
Desmoglein
Gap junction
Hemidesmosome
Tight junction
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Cut-to-the-chase Answer (0:42):
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HY USMLE Answer (5:57):
