Audio Qbank – Q240 – A 31F with epistaxis

 

A 31-year-old woman comes to the physician because of a two-day history of epistaxis and fatigue. Serum creatinine is 3.8 mg/dL. Antibody screening yields positive titers against anti-proteinase 3. A renal biopsy is shown.

Which of the following combinations of findings is most likely to be seen in this patient?

c-ANCA; ↑ Bleeding time; ↓ Platelet count
c-ANCA; ↑ Bleeding time; ↔ Platelet count
c-ANCA; ↔ Bleeding time; ↓ Platelet count
c-ANCA; ↔ Bleeding time; ↓ Platelet count
p-ANCA; ↑ Bleeding time; ↓ Platelet count
p-ANCA; ↑ Bleeding time; ↔ Platelet count
p-ANCA; ↔ Bleeding time; ↓ Platelet count
p-ANCA; ↔ Bleeding time; ↓ Platelet count