A 3-year-old boy is brought to hospital because of severe pain and distortion of his right arm. His sclerae show no abnormalities. An x-ray of the patient’s humerus is shown.
The deficient enzyme responsible for this patient’s condition bears isoforms that can be inhibited by a diuretic. Which of the following combinations of urinary findings are expected in a patient who commences this diuretic?
↑ HCO3–; ↑ pH; ↑ osmolality
↑ HCO3–; ↑ pH; ↓ osmolality
↑ HCO3–; ↓ pH; ↑ osmolality
↑ HCO3–; ↓ pH; ↓ osmolality
↓ HCO3–; ↑ pH; ↑ osmolality
↓ HCO3–; ↑ pH; ↓ osmolality
↓ HCO3–; ↓ pH; ↑ osmolality
↓ HCO3–; ↓ pH; ↓ osmolality
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Cut-to-the-chase Answer (0:54):
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HY USMLE Answer (7:23):
