Audio Qbank – HY USMLE Q #346 – Hematology

A 4-year-old boy is brought to the physician for a well-child examination. He is active and healthy with no past medical history. Physical examination shows no abnormalities. His diet consists of vegetables, fish, and chicken, but no read meat. Laboratory studies show:

Hb                                                                      10.1 g/dL
MCV                                                                 66 μm3
WBC                                                                 7,000/μL
Platelets                                                         250,000/μL
Red cell distribution width                  11% (NR 13-15%)
Hemoglobin electrophoresis              No abnormalities
Direct antiglobulin test                          Negative

Which of the following is the most likely diagnosis?

α-thalassemia
β-thalassemia
Glucose-6-phosphate dehydrogenase deficiency
Hemolytic anemia
Iron deficiency anemia