An 81-year-old man with a history of alcoholism is admitted to hospital after a recent fall. He has not seen a physician in many years. On examination, he has many ecchymoses and abrasions. He has edentulism and hemorrhagic macules around hair follicles on the upper and lower extremities. Which of the following best explains the findings in this patient?
Defective glycoprotein that forms a sheath around elastin
Defective polypeptide hydroxylation
Diminution of elastin cross-linking capacity
Disruption of clotting factor carboxylation
Inhibition of epoxide reductase
