A 23-year-old man comes to the physician for a 2-month history of pain and swelling of his distal left femur. Alkaline phosphatase activity is 1300 U/L (NR 50-150). X-ray shows spiculated new bone formation and subperiosteal elevation.
Which of the following is the most likely explanation for these findings?
c-myc gene mutation
Rb gene mutation
t(8;14) translocation
t(9;22) translocation
t(11;22) translocation
t(14;18) translocation
t(15;17) translocation
22q11 deletion
