A 24-year-old man comes to the physician for a 2-day history of dry cough. Temperature is 100 F. Serum cold agglutinins are positive. A chest x-ray shows patchy interstitial infiltrates in both lobes.
The most appropriate empiric therapy for this patient has which of the following mechanisms of action?
Formation of toxic metabolites that damage DNA
Inhibition of 30S ribosomal subunit
Inhibition of 50S ribosomal subunit
Inhibition of CD20
Inhibition of dihydrofolate reductase
Inhibition of dihydroorotate dehydrogenase
Inhibition of neuraminidase
Inhibition of viral uncoating