A 2-month-old boy with classic galactosemia is brought to the pediatrician for a 2-day history of irritability and poor feeding. Temperature is 103 F. Blood pressure is remarkably low. Blood cultures show the presence of E. coli. Binding of which of the following molecular targets is the most likely explanation for these findings?
Adenylyl cyclase
CD28
CD80/86 (B7-1/B7-2)
Elongation factor II
Guanylyl cyclase
MHC-II and T-cell receptor
Toll-like receptor
