Audio Qbank – HY USMLE Q #433 – Renal

A previously healthy 54-year-old man comes to the physician because of intermittent fever and fatigue during the past month. He has had a 10-pound weight loss during this time. There is a right foot drop. Antibody titers against myeloperodixase are positive. Laboratory studies and a renal biopsy are shown:

ESR                                                                    Elevated
Urine blood                                                   2+
Urine protein                                               2+

Which of the following is the most likely explanation for these findings?

Eosinophilic granulomatosis with polyangiitis
Goodpasture syndrome
Granulomatosis with polyangiitis
Membranoproliferative glomerulonephritis
Microscopic polyangiitis