A previously healthy 31-year-old man comes to the physician for a 4-month history of headaches. The headaches now occur almost daily. Blood pressure is 125/80. Cardiopulmonary examination shows no abnormalities. Two years ago he was treated for a kidney stone. His father had a cancer removed from his neck 20 years ago. The most appropriate pharmacologic therapy for this patient’s headaches has which of the following mechanisms of action?
Angiotensin-converting enzyme inhibition
α-blockade
β-blockade
Calcium channel inhibition (dihydropyridine)
Calcium channel inhibition (non-dihydropyridine)
Guanylyl cyclase upregulation
