A 3-year-old girl is brought to the pediatrician because she has been vomiting throughout the night. Examination is unremarkable except for dry mucous membranes and lethargy. Serum studies are as follows:
Na+: 140 mEq/L
K+: 6.4 mEq/L
HCO3–: 18 mEq/L
Glucose: 50 mg/dL
17-hydroxyprogesterone: Elevated
Which of the following is most likely deficient in this patient?
11β-hydroxylase
17α-hydroxylase
21-hydroxylase
ACTH
Desmolase
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Cut-to-the-chase Answer (0:34):
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HY USMLE Answer (6:18):