A 22-year-old man comes to the physician for a follow-up examination because of a 7-year history of calcium oxalate urolithiasis. The physician recommends increased consumption of water, as well as a pharmacologic agent to help decrease recurrence of stones. What’s the most likely mechanism of action of this drug?
Decreases calcium absorption in the small bowel
Decreases phosphate concentration in the distal convoluted tubule (DCT)
Promotes calcium reabsorption in the early-DCT
Promotes calcium reabsorption in the late-DCT
Promotes stone dissolution via acidification in the late-DCT
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Cut-to-the-chase Answer (0:58):
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HY USMLE Answer (7:04):