A 9-year-old boy is brought to the GP by his mother because of a one-week history of intense thirst and a 2-kg (4.4-lb) weight loss. He is at the 80th percentile for height and 60th percentile for weight. Physical examination shows tachypnea and dry mucous membranes. Laboratory studies show a serum bicarbonate of 17 mEq/L. If a biopsy were performed from the patient’s pancreas, which of the following would be the most likely findings?
Amyloid deposition and reduction of cell mass
Atrophy and fibrosis
Enlarged β-islet cells and nuclei
Lymphocytic infiltration and cellular necrosis
Thickening of basement membranes
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Cut-to-the-chase Answer (0:50):
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HY USMLE Answer (7:51):
