Audio Qbank – Q257 – A 25M with confusion

 

A 25-year-old man presents to emergency for a two-day history of confusion. Temperature is 103 F. He had a renal transplant at the age of 18 for crescentic glomerulonephritis secondary to granulomatosis with polyangiitis. A mucicarmine stain of the causal organism is shown.

A pharmacologic agent that targets which of the following is most appropriate for this patient?

14α-demethylase
β-1,3-glucan synthase
Ergosterol
Squalene epoxidase

Tubulin