A 20-year-old woman presents to the physician because of a one-week history of fatigue. Laboratory studies show:
Hb 9.4 g/dL
Hct 28.2%
RBC 2,3-bisphosphoglycerate 9000 nmol/mL (N = 4100)
Bilirubin (total) 8 mg/dL
Bilirubin (indirect) 6.7 mg/dL
The patient’s blood smear is shown.
The deficient enzyme in this patient acts on which of the following substrates?
Acetyl-CoA
Lactate
Oxaloacetate
Phosphoenolpyruvate
Pyruvate
UDP-glucuronosyltransferase
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Cut-to-the-chase Answer (0:40):
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HY USMLE Answer (7:39):