A 51-year-old woman comes to the GP because of pain in her left great toe. Vitals are within normal limits. She has a 5-year history of type II diabetes mellitus managed with glipizide. She reports various drug allergies. Surgical history is remarkable for appendectomy 2 years ago, hysterectomy 7 years ago for symptomatic uterine fibroids, nasal surgery 9 years ago for stridor, and ACL repair 17 years ago. Physical examination shows marked tenderness, erythema, and swelling of the first metatarsophalangeal joint on the left foot. Arthrocentesis is performed and shown below.
Which of the following pharmacologic agents is the most appropriate acute management?
Acetaminophen
Allopurinol
Colchicine
Indomethacin
Prednisone
Rasburicase
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Cut-to-the-chase Answer (1:04):
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HY USMLE Answer (7:22):
