A 32-year-old woman presents to the GP because of a 2-day history of burning sensation with urination. Temperature is 99.5 F. An organism is cultured from the urine that demonstrates resistance to ampicillin but sensitivity to ceftriaxone. Which of the following best explains this antimicrobial resistance pattern as exhibited by the causal organism?
Decreased influx
Increased efflux
Methylation of beta-lactam ring
Production of cleavage enzyme
Synthesis of novel penicillin-binding protein
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Cut-to-the-chase Answer (0:38):
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HY USMLE Answer (6:31):
