A 4-year-old girl is brought to the physician because of a 4-day history of itchy, cutaneous papules on her inner thighs. She presented 6 months earlier with similar papules on her inner arm. KOH prep of one of the lesions shows pseudohyphae and single-budding yeast. Skin antigen testing is performed and shows normal response to Candida protein extract. A nitroblue-tetrazolium assay reveals a blue color. Which of the following is the most likely explanation for these findings?
Deficiency of mucosal immunoglobulin
Deficiency of cell-mediated immunity
Impaired leukocyte adhesion
Inability to produce superoxide
Reduction in hydroxyl-halide radicals
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Cut-to-the-chase Answer (0:42):
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HY USMLE Answer (7:43):
