A 985-gram female newborn delivered at 27 weeks gestation develops subcostal retractions, grunting, and rapid breathing during the first minute of life. Auscultation of the chest demonstrates coarse rhonchi. CXR shows a reticulogranular appearance. ABG shows high pCO2, low pO2, and low pH. A deficiency of which of the following is most likely responsible for this patient’s presentation?
Lecithin
Phosphatidylinositol
Pulmonary citrate/saline ratio
Sphingomyelin
Surfactant protein D
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Cut-to-the-chase Answer (0:38):
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HY USMLE Answer (4:07):