Audio Qbank – Q88 – A 34F with chills and red urine

A 34-year-old man comes to the GP because of a 6-day history of chills and red urine. He has a 4-year history of chronic sinusitis and has a long history of sinus obstruction for which he has undergone many operations. Rhinoscopy shows a diminished nasal septum. CXR shows pulmonary nodularity. Which of the following is most likely seen in this patient?

 

  c-ANCA; anti-GBM antibodies
  c-ANCA; anti-MPO antibodies
  c-ANCA; anti-PR3 antibodies
  p-ANCA; anti-GBM antibodies
  p-ANCA; anti-MPO antibodies
  p-ANCA; anti-PR3 antibodies

 

Cut-to-the-chase Answer (0:53):
HY USMLE Answer (4:17):