A 9-year-old boy is brought to emergency for a 5-day history of bloody diarrhea. He has had generalized fatigue for 3 days. Temperature is 98.6 F. Examination shows scleral icterus and pallor. Laboratory studies show:
Hemoglobin 7 g/dL
MCV 85 fL
Leukocytes 19,000/μL
Platelets 60,000/μL
Coombs test Negative
Which of the following is the most likely explanation for these findings?
Cold autoimmune hemolytic anemia
Glucose-6-phosphate dehydrogenase deficiency
Hemolytic uremic syndrome
Shigellosis
Thrombotic thrombocytopenic purpura
