A 69-year-old man comes to the physician because of a 6-month history of increasing fatigue. He has had a 15-kilogram weight loss during this time.
Which of the following is the most likely explanation for these findings?
Direct extension and seeding of head of pancreas adenocarcinoma
Hematogenous dissemination of ascending colorectal cancer
Lymphogenous spread of small cell bronchogenic carcinoma
Primary hepatocellular carcinoma
Primary hepatic angiosarcoma