A 38-year-old woman comes to the physician for a follow-up examination. She has a 6-month history of generalized pruritus. Physical examination shows mild scleral icterus. Laboratory studies show elevated direct bilirubin and alkaline phosphatase. Her brother has rheumatoid arthritis. Which of the following is most likely to be seen in this patient?
Anti-microsomal antibodies
Anti-smooth muscle antibodies
Hypercholesterolemia
Hypoalbuminemia
Prothrombin time elevation