A 6-month-old boy is brought to the physician by his mother for a 2-week history of an ophthalmologic abnormality she’s noticed in certain lighting. Which of the following is most likely to be seen in this patient?
Activation of proto-oncogene
Autosomal recessive inheritance
Development of osteosarcoma
Development of Paget disease of bone
Insufficient hexosaminidase-A activity
