A 46-year-old man is brought to emergency by police after being found on a park bench disoriented. He is unkempt. Physical examination shows ataxia, confusion, and left-sided ophthalmoplegia. The deficient cofactor in this patient also plays a role in which of the following?
Acetyl-CoA carboxylase
Fumarate hydratase
Methionine synthase
Thymidylate synthase
Transketolase
