HY USMLE Q #1075 – Pathology

A 12-year-old boy is brought to the physician for a 2-day history of progressive swelling of the eyes. He has no past medical history. Vitals are normal. Physical examination shows mild infraorbital and pedal edema bilaterally. There is no abdominal fluid wave. Laboratory studies show:

Complement protein C3                                                                   150 mg/dL (NR 88-201)
Complement protein C4                                                                   40 mg/dL (NR 16-48)
ALT                                                                                                                 35 U/L
AST                                                                                                                30 U/L
Urine protein                                                                                           2+
Urine RBC                                                                                                 0-1/hpf

Which of the following is most likely to be seen in this patient?

  Antibody-antigen immune complexes (subendothelial)
  Antibody-antigen immune complexes (subepithelial)
  Hyaline deposition within the mesangium
  IgA deposition within the mesangium
  Increased serum LDL