A 36-year-old woman comes to the physician for a follow-up appointment. She has a 5-year history of rheumatoid arthritis. It was initially managed with diclofenac, esomeprazole, methotrexate, and occasional prednisone. She had a peptic ulcer one year ago that fully resolved with temporary cessation of the diclofenac and replacement with acetaminophen. Her daily esomeprazole dosage was also increased. The acetaminophen, however, did not provide adequate arthritic relief during this time. Her current pharmacologic regimen is ibuprofen, esomeprazole, methotrexate, misoprostol, and occasional prednisone. She does not have any current ulcers. Which of the following best reflects the role and mechanism of action of misoprostol in this patient?
Primary prevention; foveolar cell binding; stimulates mucous and bicarbonate production
Primary prevention; parietal cell binding; stimulates mucous and bicarbonate production
Primary prevention; parietal cell binding; decreases gastric acid production
Secondary prevention; foveolar cell binding; stimulates mucous and bicarbonate production
Secondary prevention; parietal cell binding; stimulates mucous and bicarbonate production
Secondary prevention; parietal cell binding; decreases gastric acid production
Tertiary prevention; foveolar cell binding; stimulates mucous and bicarbonate production
Tertiary prevention; parietal cell binding; stimulates mucous and bicarbonate production
Tertiary prevention; parietal cell binding; decreases gastric acid production
