A 51-year-old woman comes to the physician for a 2-month history of worsening rash on the dorsum of both hands. BMI is 32. She does not smoke or drink. She has hypertension managed with hydrochlorothiazide. Her brother has rheumatoid arthritis. Which of the following is most likely to be seen in this patient?
Anti-microsomal antibodies
Anti-mitochondrial antibodies
Anti-phospholipid syndrome
Hamartomatous colonic polyps
Ovarian serous cystadenocarcinoma