A 17-year-old girl comes to the physician because of not having had a menstrual period for the past 6 months. Her menses started at age 13 and occurred at regular, 28-day intervals until this point. She is an avid long-distance runner, sometimes running over 100 miles in a week. BMI is 16.5. Vitals are normal. Which of the following is most likely to be seen in this patient?
↑ Osteoclast activity; ↑ Leptin; ↑ GnRH pulsation; ↑ FSH
↑ Osteoclast activity; ↑ Leptin; ↓ GnRH pulsation; ↑ FSH
↑ Osteoclast activity; ↑ Leptin; ↑ GnRH pulsation; ↓ FSH
↑ Osteoclast activity; ↑ Leptin; ↓ GnRH pulsation; ↓ FSH
↑ Osteoclast activity; ↓ Leptin; ↑ GnRH pulsation; ↑ FSH
↑ Osteoclast activity; ↓ Leptin; ↑ GnRH pulsation; ↓ FSH
↑ Osteoclast activity; ↓ Leptin; ↓ GnRH pulsation; ↑ FSH
↑ Osteoclast activity; ↓ Leptin; ↓ GnRH pulsation; ↓ FSH
↓ Osteoclast activity; ↑ Leptin; ↑ GnRH pulsation; ↑ FSH
↓ Osteoclast activity; ↑ Leptin; ↓ GnRH pulsation; ↑ FSH
↓ Osteoclast activity; ↑ Leptin; ↑ GnRH pulsation; ↓ FSH
↓ Osteoclast activity; ↑ Leptin; ↓ GnRH pulsation; ↓ FSH
↓ Osteoclast activity; ↓ Leptin; ↑ GnRH pulsation; ↑ FSH
↓ Osteoclast activity; ↓ Leptin; ↑ GnRH pulsation; ↓ FSH
↓ Osteoclast activity; ↓ Leptin; ↓ GnRH pulsation; ↑ FSH
↓ Osteoclast activity; ↓ Leptin; ↓ GnRH pulsation; ↓ FSH
